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Summary list of studies added recently but with incomplete data.

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ISRCTNAcronym & TitleStatusTypeOpen to additional sites
 A comparative ethnographic investigation into the culture, organisation, management techniques and e - A comparative ethnographic investigation into the culture, organisation, management techniques and environmental features of high-secure mental health units   
 A comparison of FES and AFO for the treatment of foot drop in mS - A qualitative, quantitative and cost utility comparison of Functional Electrical Stimulation and Ankle Foot Orthoses in the management of foot drop in Multiple SclerosisIn Set-Up NHS Permission ReceivedInterventionalNo
 A longitudinal study of adolescent outcomes and CU in a sample of clinically referred children with - A longitudinal study of adolescent outcomes and CU in a sample of clinically referred children with Attention deficit hyperactivity disorderOpenObservational 
 A randomised, controlled trial to determine the median effective concentration of bupivacaine, levob - A randomised, controlled trial to determine the median effective concentration of bupivacaine, levobupivacaine and ropivacaine after intrathecal and extradural injection for pain relief in the first stage of labour.ClosedInterventionalN/A
 aaaTestStudy_LT - aaaTestStudy_LT test recordIn Set-Up NHS Permission ReceivedInterventionalYes, within lead country only
 ACES Art as Creative Engagement for Stroke - Can an arts based creative engagement intervention following stroke improve psychosocial outcomes? A feasibility trial of a creative engagement intervention for in-patient rehabilitationIn Set-Up Pending NHS Permission  
 Active Assistance for Psychological Therapy (ACTISSIST) - Active Assistance for Psychological Therapy (Actissist): Using mobile technology to deliver cognitive behaviour therapy for psychosisIn Set-Up Pending NHS Permission  
 ADHD in children with learning difficulties - ADHD in children with learning difficultiesOpenObservational 
 Advanced Nurses Contribution to HIV Services (ANCHIVS) - An examination of HIV service delivery in England and the contribution of nurses in advanced practice rolesIn Set-Up Pending NHS Permission  
 Analysis of 24/7 working in the London hyper acute stroke system - Analysis of 24/7 working in the London hyper acute stroke systemIn Set-Up Pending NHS Permission  
 Aneurysm CaRe Trial - Cardiac rehabilitation after aneurysm repair 1.0 - Pilot Randomised Controlled Trial of Cardiac Rehabilitation vs. Standard Care after Aortic Aneurysm Repair to reduce Adverse Cardiovascular EventsIn Set-Up Pending NHS PermissionInterventionalNo
 Anti inflammatory effects of Keratinocyte growth factor in acute lung injury - Anti inflammatory effects of keratinocyte growth factor in acute lung injury in healthy volunteersIn Set-Up Pending NHS Permission  
 Anti-angiogenic agent in neuroblastoma - Assessment of therapeutic potential of a new anti-angiogenic agent in neuroblastomaIn Set-Up NHS Permission Received  
 BLIS - Barriers to life style interventions in schizophreniaIn Set-Up Pending NHS Permission  
 Can aldosterone predict sinus after treatment of AF? - Does aldosterone predict maintenance of normal sinus rhythm after treatment of atrial fibrillation?   
 CATALyST - Neighbourhood determinants of the common mental disorders: the Caerphilly Health and Social Needs Longitudinal StudyOpen  
 CATH-B Chinese community Access to Treatment for Hepatitis B - Identifying and addressing barriers to healthcare access for Hepatitis B in UK Chinese populations. (CATH-B Chinese community Access to Treatment for Hepatitis B)In Set-Up Pending NHS PermissionObservationalYes, within lead country only
 Catheter ablation of typical right atrial flutter under MR guidance. - Catheter ablation of typical right atrial flutter under MR guidance.In Set-Up Pending NHS PermissionInterventionalNo
 CiPHER - Phase II multicentre study assessing the efficacy of Cabazitaxel in Patients with HER2-negative metastatic breast cancer and having unresectable brain metastasesIn Set-Up Pending NHS PermissionInterventional 
63375144CLARET - CLL Levels following Alemtuzumab in Responders to Earlier Therapy: A randomised phase III study to assess alemtuzumab consolidation therapy in patients with CLL who have responded to previous therapy.In Set-Up NHS Permission ReceivedInterventionalYes, within lead country only
 Cognitive and neurobiological mechanism leading to psychotic traits in adolescents with ADHD: develo - Cognitive and neurobiological mechanism leading to psychotic traits in adolescents with ADHD: developing an evidence base for intervention strategiesIn Set-Up Pending NHS Permission  
 COMET - Choice Of Moisturiser in Eczema Treatment (COMET): A feasibility study of pragmatic, single blind, randomised clinical trial to compare the clinical and cost effectiveness of leave-on emollients in treatment of infant eczema in primary careIn Set-Up Pending NHS Permission  
 Community pharmacists optimising treatment for patients with psoriasis - Is it feasible for community pharmacists to deliver an educational programme designed to help people with psoriasis self-manage as effectively as possible?In Set-Up Pending NHS Permission  
 ComPAKT: A Phase I trial of olaparib in combination with AZD5363 - ComPAKT: A Phase I multicentre trial of the combination of olaparib (PARP inhibitor) and AZD5363 (AKT inhibitor) in patients with advanced solid tumoursIn Set-Up Pending NHS PermissionInterventional 
 Complementary therapies and supportive care - Research Proposal: Complementary therapies and supportive cancer care: towards integration and holistic care? A qualitative study of patients and professionalsIn Set-Up NHS Permission Received  
 CONCEPTT Newborn Study - Glucose Control and metabolic adaptation in offspring of women with Type 1 Diabetes recruited to the CONCEPTT Study.In Set-Up NHS Permission ReceivedObservationalNo
 Dementia in the workplace - Dementia in the workplace: a feasbility study exploring the employment related experiences of people with dementia or mild cognitive impairment and their employers and coworkers to identify the potential for continued employment postdiagnosisOpenObservationalNo
 Detecting chromosomal anomalies with attention deficit hyperactivity disorder and learning disabilit - Detecting chromosomal anomalies with attention deficit hyperactivity disorder and learning disability using microarray based comparative genomic hybridisationOpenObservational 
 Development of a tumour radiosensitivity-associated gene expression signature - Development of a tumour radiosensitivity-associated gene expression signatureClosed N/A
 Diabetes 001 (LRN East) - Influence of maternal glucose tolerance in pregnancy on parity-related and normal variation in size at birth; investigation of genetic determinantsIn Set-Up Pending NHS PermissionObservationalNo
 Diabetes 019 (LRN NWLon) - A trial to compare the effects of nebivolol versus atenolol on various cardiovascular measurements including insulin sensitivityIn Set-Up Pending NHS Permission  
 DIAMOND-Lewy Work Package 1, version 1.0 19.08.13 - Improving the diagnosis and management of neurodegenerative dementia of Lewy body type in the NHS (DIAMOND-Lewy): Work package 1In Set-Up Pending NHS PermissionObservational 
 DIAMOND-Lewy Work Package 2: Embedded qualitative studies - Improving the diagnosis and management of neurodegenerative dementia of Lewy body type in the NHS (DIAMOND-Lewy): Work package 2: Exploring and understanding barriers to improving the diagnosis and management of Lewy body dementias.In Set-Up Pending NHS PermissionObservational 
 Dietary requirement for vitamin D in adolescents aged 14-18years - A dose-response, double-blind, randomised placebo-controlled trial to estimate the dietary requirement for vitamin D in male and female adolescents aged 14-18years (The ODIN Study)In Set-Up Pending NHS PermissionInterventional 
 Disentangling genetic, intrauterine and environmental factors on childhood psychopathology using a n - Disentangling genetic, intrauterine and environmental factors on childhood psychopathology using a novel methodOpenObservational 
 DRN 850 TrialNet LIFT Study - Long Term investigative Follow-up in TrialNet (LIFT)   
 DRN 900 - study diabetesIn Set-Up Pending NHS PermissionObservational 
 Early evaluation of the Integrated Care and Support Pioneers - Early evaluation of the Integrated Care and Support ‘Pioneers’ in the context of the Better Care Fund and the Integrated Care Policy ProgrammeIn Set-Up Pending NHS Permission  
 Early predictor of violence - Early predictor of violenceOpenObservational 
 EaStER Main trial - EaStER: Early Stage Glottic Cancer: Endoscopic Excision or Radiotherapy?Suspended Yes, within and outside lead country
 Effect of Exercise on Neutrophil Function in Patients with COPD - A Pilot Study to examine the Effect of Acute Exercise on Neutrophil Function in patients with Chronic Obstructive Pulmonary Disease.In Set-Up Pending NHS PermissionObservationalNo
 EORTC 90091-10093 - Trastuzumab in HER2-negative Early breast cancer as Adjuvant Treatment for Circulating Tumour Cells (CTC) ("Treat CTC" trial)In Set-Up Pending NHS Permission  
 EORTC Clinical Trial 10994 - EORTC Clinical Trial 10994 - BIG p53 First Prospective Intergroup Translational Research Trial Assessing Predictive Value of p53 Using a Functional Assay in Patients with Locally Advanced Inflammatory or Large Operable Breast Cancer Prospectively RandomisClosedObservationalN/A
 EORTC Generic QL Questionnaire Development Phases I to III - Thyroid - EORTC Generic Module Development: Phases I to III of the development process for disease or domain specific quality of life questionnaires - ThyroidIn Set-Up Pending NHS PermissionObservational 
 EORTC Quality of Life Module for patients with vulva cancer - Phase 3-4 development of a questionnaire to address treatment morbidity and assess the quality of life following treatment for vulva cancerIn Set-Up Pending NHS PermissionObservational 
 EPIFEVER - EPIFEVER: Elucidating molecular mechanisms underlying epidural related maternal fever.In Set-Up Pending NHS PermissionObservationalNo
 Epigenetic biomarkers in HNSCC - Epigenetic biomarkers in Head and Neck Squamous Cell Carcinoma surgical margin analysisIn Set-Up NHS Permission Received  
 EPOCH phase 2 qualitative evaluation - Enhanced Peri-Operative Care for High-risk patients (EPOCH) Study: Phase 2 qualitative evaluationIn Set-Up Pending NHS PermissionObservationalNo
 Examining Sonographer visuospatial perception and psychomotor ability. - Is there a relationship between ultrasound scanning ability and visuospatial perception and psychomotor ability?OpenObservationalNo
 Factors mediating the effects of prison environment on mental health - Factors mediating the effects of prison environment on mental healthOpenObservational 
 Feasibility study of psychopathology in children with 22Q11 deletion syndrome (22Q11DS) - Feasibility study of psychopathology in children with 22Q11 deletion syndrome (22Q11DS)In Set-Up Pending NHS Permission  
 Feasibility study of YP Face IT - A feasibility study to inform an RCT to evaluate an online psychosocial intervention for young people with appearance-altering conditions (YP Face IT)In Set-Up Pending NHS Permission  
 FILTR Study Field - A Prospective Observational Study of the Diagnostic Accuracy of an Ambulance triage Tool for Ruptured Aortic AneurysmsIn Set-Up Pending NHS PermissionObservationalYes, within lead country only
 Focus Group for Envisage Project - Focus group with participants from the Envisage Project to inform future use of biomechanical visualisations in stroke rehabilitation   
 Frailty in Older Patients Admitted for Emergency Surgery - Evaluating the feasibility of measuring frailty and the impact of the frailty syndrome on postoperative outcomes in older patients admitted for emergency surgeryIn Set-Up Pending NHS PermissionObservationalNo
 GAN Cymru - Collaborative study to identify genes associated with susceptibility to anorexia nervosaOpenObservational-unknown-
 GEM (EORTC 08114) - Genetics of EGFR Mutation Study (GEM): a Translational Study of the EORTC Lung GroupIn Set-Up Pending NHS Permission  
 General Practitioners Views on Post-Surgical Outcomes - To Explore General Practitioners Views on Post-Surgical Outcomes utilising a Consensus Delphi MethodologyIn Set-Up Pending NHS Permission  
 Genetic analysis of ocular-eyelid colobomata and facial clefts - Genetic analysis of patients with ocular-eyelid colobomata and facial clefts to understand the molecular mechanisms of embryonic fissure closureIn Set-Up Pending NHS PermissionObservationalNo
 Genetic dissection of the mood-psychosis spectrum - Genetic dissection of the mood-psychosis spectrumOpenObservational 
 Genetic susceptibility to a deficit in contextual processing across the schizophrenia/bipolar disord - Genetic susceptibility to a deficit in contextual processing across the schizophrenia/bipolar disorder diagnostic divideIn Set-Up NHS Permission Received  
 GENPROS. - GENPROS - Analysing outcomes after prostate cancer diagnosis and treatment in carriers of rare germline mutations in cancer predisposition genesIn Set-Up Pending NHS PermissionObservational 
 Glucophage in Type-1 Diabetes Study - Effectiveness of Glucophage® SR as an adjunct to insulin in improving glycaemic control, without increasing the episodes of hypoglycaemia, in non-overweight patients with type-1 Diabetes.OpenInterventionalNo
 GOG-0242 - A PHASE II STUDY TO DETERMINE THE RESPONSE TO SECOND CURETTAGE AS INITIAL MANAGEMENT FOR PERSISTENT LOW RISK, NON-METASTATIC GESTATIONAL TROPHOBLASTIC NEOPLASIAIn Set-Up NHS Permission Received  
 GSAO - A Phase I trial of intravenous GSAO (Protocol PH1/109)In Set-Up NHS Permission Received  
 HAPO FAMILY - HAPOIn Set-Up Pending NHS Permission  
 Heart failure revascularization - Heart failure revascularization trial UK (HEART UK)    
 High­-resolution connectivity of the basal ganglia in health & disease - Imaging of the human basal ganglia in health and disease using high resolution MRI.In Set-Up Pending NHS PermissionObservational 
 HIIT in PR for ILD; a feasibility study - Feasibility of high intensity interval training in pulmonary rehabilitation programmes for patients with interstitial lung disease and preliminary efficacy of its long-term benefits.In Set-Up Pending NHS PermissionInterventionalYes, within lead country only
 HITS-NS Feasibility Trial Nested Qualitative Study - Head Injury Transportation Straight to Neurosurgery (HITS-NS) Trial Nested Qualitative StudyIn Set-Up Pending NHS PermissionObservationalNo
 Home Administered Pre-surgical Psychological Intervention for Knee OA - Home Administered Pre-surgical Psychological Intervention for Knee Osteoarthritis: A single blind feasibility randomised controlled trialIn Set-Up Pending NHS Permission  
 HYPREL - A feasibility study of relaxation therapy plus autohypnotherapy (HYPREL) for patients with thoracic cancer undergoing radiotherapyIn Set-Up NHS Permission Received  
 ICON3 p53 - Evaluation of p53 mutation as a predictive factor in outcome to chemotherapy in ovarian cancer. (“ICON3 p53 study”)In Set-Up NHS Permission Received  
 Identifying susceptibility genes for ADHD with antisocial behaviour as a covariate - Identifying susceptibility genes for ADHD with antisocial behaviour as a covariateIn Set-Up Pending NHS Permission  
 IELSG10 - A phase II study of CHOP, Rituximab, intrathecal methotrexate followed by radiotherapy in patients with primary testicular Non-Hodgkin's LymphomaClosed N/A
 iMAP2 - A randomised controlled trial comparing two pertussis-containing vaccines in pregnancy and vaccine responses in UK mothers and their infants (immunising Mums Against Pertussis, iMAP2)In Set-Up Pending NHS PermissionInterventionalNo
 IM-CAT - Immunotherapy for squamous cell carcinoma of the head and neck by TransimmunizationIn Set-Up NHS Permission ReceivedInterventionalYes, within lead country only
 IMMUNOTACE - A randomised phase II clinical trial of conditioning cyclophosphamide and chemoembolisation with or without vaccination with dendritic Cells pulsed with HepG2 lysate in vivo in patients with Hepatocellular CarcinomaIn Set-Up Pending NHS PermissionInterventional 
 Improving post hypoglycaemic follow-up care - An assessment of the feasibility, and potential impact of a dual intervention to improve self-referral rates to diabetic care following hypoglycaemic emergencies.Closed N/A
 Increasing uptake of NHS Health Checks in Northamptonshire - Assessing the impact of different invitation letters on uptake of the NHS Health Check in NorthamptonshireIn Set-Up Pending NHS Permission  
 Individually Ventilated Cages and prevention of lab animal allergy - Individually Ventilated Cages in laboratory animal facilities and the prevention of laboratory animal allergy; a proof-of-concept studyIn Set-Up Pending NHS PermissionObservationalNo
 INjection versus SplinTing in Carpal Tunnel Syndrome (INSTinCTS) - The clinical and cost effectiveness of of a steroid injection versus a night splint for Carpal Tunnel Syndrome: a pragmatic randomised trial in primary careIn Set-Up Pending NHS Permission  
 INPIC Pilot: Cordotomy - The role of cordotomy in the management of mesothelioma-related pain in the United KingdomIn Set-Up NHS Permission Received  
 Investigating genetic and environmental risk factors for sub-clinical psychosis like symptoms in bir - Investigating genetic and environmental risk factors for sub-clinical psychosis like symptoms in birth cohort studyOpenObservational 
 Investigating immunogenicity to biopharmaceutics version 2 - Anti-Biopharmaceutical Immunization: prediction and analysis of clinical relevance to minimize the RISKIn Set-Up Pending NHS PermissionObservationalYes, within lead country only
 Knee Pain and Related Health in the Community Study - Knee Pain and Related Health in the Community StudyIn Set-Up Pending NHS Permission  
 Lirabose-1 - A comparative study of the effects of Liraglutide and Acarbose on glycaemic control, weight and Health Related Quality Of Life (HRQOL) in Overweight type 2 Diabetic patients on Oral Hypoglycaemic Agents (OHAs) + high doses of insulin.OpenInterventionalNo
 LV Endocardial Cardiac Resynchronisation Therapy - A randomised double-blinded cross over study to evaluate the improvement of left ventricular systolic failure using targeted left ventricular endocardial lead placement in cardiac resynchronisation therapy. (EndoCRT)In Set-Up Pending NHS PermissionInterventionalNo
 LYDO (Thome) - A Long Term Study of a Medication for Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)OpenInterventional 
 MARCHON - A randomised 3-arm trial of modestly accelerated radiotherapy alone or with either synchronous nimerazole or synchronous cisplatinum chemotherapyClosed N/A
 Methods of ovarian tissue culturing for fertility preservation - In Vitro Culture and Maturation of Ovarian Tissue and Follicles: Follicle Microenvironment Engineering as a tool to study folliculogenesis and provide fertility preservation.In Set-Up Pending NHS PermissionObservationalNo
 METILDA - A Randomised Phase II Study in Metastatic Melanoma to Evaluate the Efficacy of Adoptive Cellular Therapy with Tumour Infiltrating Lymphocytes (TIL) and Assessment of High versus Low Dose Interleukin-2In Set-Up NHS Permission ReceivedInterventional 
 Microanatomical correlation - Microanatomical correlation between dynamic MRI and histopathology in women with operable breast cancerIn Set-Up NHS Permission Received  
 Mind-mindedness Intervention - Assessing the efficacy of an intervention to improve mind-mindedness in teenage mothers.In Set-Up Pending NHS PermissionInterventionalYes, within lead country only
 MINI - A MINI perspective: needs assessment for common mental disorders in primary care.OpenObservationalNo
 Mobility, Mood and Place - Mobility, Mood and Place   
 Molecular genetic studies of schizophrenia - Molecular genetic studies of schizophreniaOpenObservational 
 Monitoring Scoliosis with 3D Ultrasound - Monitoring and predicting the curve progression of patients with adolescent idiopathic scoliosis using three-dimensional ultrasoundIn Set-Up Pending NHS PermissionObservationalNo
 Msk Evaluation - Evaluation of the redesigned NHS Lanarkshire Musculoskeletal Service   
 NEOBLADE - Phase II randomised placebo controlled NEOadjuvant chemotherapy study of Nintedanib with Gemcitabine and Cisplatin in locally advanced muscle invasive BLADder cancErIn Set-Up Pending NHS PermissionInterventionalYes, within and outside lead country
 OPIP - Medium Cost Effectiveness of Automated Non-Invasive Ventilation Outpatient Set Up vs Standard Fixed Level Non-Invasive Ventilation Inpatient Set Up In Obese Patients with Chronic Respiratory DiseaseIn Set-Up Pending NHS PermissionInterventionalYes, within lead country only
 Optimising vegetable based convenience food production - Optimising vegetable based convenience food production to retain compounds found in vegetablesIn Set-Up Pending NHS Permission  
 Pain_OMICs - Pain_Omics - a prospective study to identify biomarkers involved in the transition from acute to persistent chronic low back painIn Set-Up Pending NHS Permission  
 Pain_Omics - Pain_Omics - a prospective study to identify biomarkers involved in the transition from acute to persistent chronic low back pain.In Set-Up Pending NHS PermissionObservational 
 Phase II trial of PR1 and WT1 peptides in Chronic Myeloid Leukaemia - A Cancer Research UK Phase II immunotherapy study of PR1169 and WT1126 peptide vaccines plus GMCSF and imiquimod given alongside second line therapy with nilotinib versus nilotinib therapy alone in patients with Chronic Myeloid Leukaemia (CML) molecularly positive for BCRABL transcript.Closed N/A
 Polymyalgia Rheumatica (PMR): a qualitative interview study - Polymyalgia Rheumatica (PMR): a qualitative interview study of general practitionersIn Set-Up Pending NHS PermissionObservationalNo
 POPPI: Feasibility Study - Psychological Outcomes following a nurse-led Preventative Psychological Intervention for critically ill patients (POPPI): Feasibility StudyIn Set-Up Pending NHS PermissionInterventionalNo
 Predicting and preventing adolescent depression - Predicting and preventing adolescent depressionOpenObservational 
 Predicting response to CRT using body surface ECG mapping - Evaluation of a novel method of non-surface electrocardiographic mapping in predicting clinical, structural and neurohormonal responses in patients undergoing cardiac resynchronization therapy.In Set-Up Pending NHS PermissionObservationalNo
 Prediction of stroke outcome using machine learning of brain images - Optimizing prediction of stroke thrombolysis outcome using brain imaging machine learningIn Set-Up Pending NHS PermissionObservational 
 PTLD1 - Title to be confirmedIn Set-Up NHS Permission Received Yes, within and outside lead country
 Qualitative Evaluation of Non Drug Interventions in Dementia - Factors influencing the translation of evidence-based non-drug interventions into routine dementia care: a qualitative study using Cognitive Stimulation Therapy (CST) as a case study.In Set-Up Pending NHS PermissionObservationalYes, within lead country only
 RADIOLOGIC - Definitive Chemoradiotherapy with the Addition of Lapatinib in Inoperable, Locally Advanced Oesophageal and OGJ Adenocarcinoma A Phase I studyClosedInterventionalN/A
 Randomised controlled trial of cortisol versus placebo for chronic post traumatic stress disorder - Randomised controlled trial of cortisol versus placebo for chronic post traumatic stress disorderIn Set-Up Pending NHS Permission  
 REACT Study: Recognition of Excessive bleeding At ChildbirTh - How much is too much? Exploring clinical recognition of excessive maternal blood loss during childbirth.In Set-Up Pending NHS PermissionInterventional and ObservationalNo
 RE-AKT - A randomised Phase II study of Enzalutamide (MDV3100) in combination with AZD5363 in Patients with Metastatic Castration Resistant Prostate CancerIn Set-Up Pending NHS PermissionInterventional 
 Recognition Perimetry Using High Pass Filtered Letter Targets - Recognition perimetry using high pass filtered letter targets in normal subjects and patients with glaucomaIn Set-Up Pending NHS PermissionObservationalYes, within lead country only
 Rehabilitation in patients newly diagnosed with inoperable lung cancer - Rehabilitation needs and acceptability of rehabilitation services in patients newly diagnosed with inoperable lung cancerIn Set-Up Pending NHS PermissionObservational 
 Respiratory and peripheral muscle function in people with lung cancer - Respiratory and peripheral muscle function in people with lung cancerIn Set-Up Pending NHS Permission  
 Retinal photography in older HIV positive adults - Using retinal photography to estimate cerebrovascular and cardiovascular health in HIV positive adults aged over fifty, HIV negative controls aged over fifty, and younger HIV positive adultsIn Set-Up Pending NHS PermissionObservational 
 Retinal photography in older HIV positive adults. - Using retinal photography to estimate cerebrovascular and cardiovascular health in HIV positive adults aged over fifty, HIV negative controls aged over fifty, and younger HIV positive adults.In Set-Up Pending NHS PermissionObservationalNo
 RIFSYS - A placebo controlled single centre double blind randomised trial to investigate the efficacy of Rifaximin versus placebo in improving systemic inflammation and neutrophil malfunction in patients with cirrhosis and chronic hepatic encephalopathyIn Set-Up Pending NHS PermissionInterventionalNo
 RITUXILUP, Version 1.0 - RITUXILUP - An open label randomised multicentre controlled trial of RITUXImab and mycophenolate mofetil (MMF) without oral steroids for the treatment of LUPus nephritisIn Set-Up Pending NHS PermissionInterventionalYes, within lead country only
 Role of cellular immune responses in inflammation of the skin v1.0 - Role of cellular immune responses in inflammation of the skinIn Set-Up Pending NHS PermissionObservationalNo
 Role of NFkB in CLL - Targeting NF-kB activation and proliferation signals in CLL.OpenInterventional and ObservationalNo
 Sample and data collection for diastolic heart failure study - Sample and data collection for diastolic heart failure study: Biomarkers for Diastolic Heart FailureIn Set-Up Pending NHS PermissionObservational 
 Satisfaction with social care amongst carers of stroke survivors - Satisfaction with social care amongst carers of stroke survivorsClosedObservationalN/A
 SIBS - A Genetic Study of Quantitative Phenotypes Related to Breast CancerIn Set-Up NHS Permission Received  
62865905SOB-LC - A randomised trial of high vs low intensity training in breathing techniques for breathlessness in patient with malignant lung disease: a feasibility studyClosedInterventionalN/A
 Sodium Valproate for GSDV Version 1.0 13th January 2014 - A Phase II pilot study to explore treatment with Sodium Valproate in Adults with McArdle Disease (Glycogen Storage Disorder Type V, GSDV)In Set-Up Pending NHS PermissionInterventionalNo
 Southall And Brent REvisited (SABRE) - SABRE V3 - Consequences of ethnic differences in cardiometabolic disease in older age: the Southall And Brent REvisited (SABRE) tri-ethnic population cohort - SABRE V3In Set-Up Pending NHS Permission  
 Spectral Analysis of Resected Brain Tissue - Spectral Analysis of Resected Brain Tissue HypErspectraL Imaging Cancer Detection (HELICoiD A)In Set-Up Pending NHS PermissionObservational 
 STRONG TREAT 1 to 4 - Randomized, Open-label, Multi Centre Phase III Clinical Trial on Multiple versus Single Dose of Ivermectin for the Treatment of StrongyloidesIn Set-Up Pending NHS PermissionInterventionalYes, within and outside lead country
 Successful drug treatment for street sex workers: a qualitative study - Exploring sex workers and service providers’ views of successful drug treatment for street sex workers: a qualitative studyIn Set-Up Pending NHS Permission  
 SYSTEMATIC: NAATS of pooled self-taken versus clinican-taken swabs - 1 - Swab-yourself trial with economic monitoring and testing for infections collectively (SYSTEMATIC): A study comparing clinician-taken versus self-taken rectal and pharyngeal samples, and separate versus pooled specimens, from each individualIn Set-Up Pending NHS PermissionObservationalNo
 TB031 BCG Challenge Study - TB031: A clinical challenge study to quantify BCG at the challenge site of healthy volunteers receiving either intradermal BCG SSI or BCG TICE at standard or high doseIn Set-Up Pending NHS PermissionInterventionalNo
 Testingsss - TestingIn Set-Up NHS Permission Received  
 The Culture of TYA Care across Five Principal Treatment Centres - The Culture of TYA Care across Five Principal Treatment Centres and their Networks: BRIGHTLIGHT Case StudyIn Set-Up Pending NHS PermissionObservational 
 The EUROpean Dyspnoea survey in EMergency departments (EURODEM study) - The EUROpean Dyspnoea survey in EMergency departments (EURODEM study)In Set-Up Pending NHS PermissionObservationalYes, within lead country only
 The Midlands and North of England Stillbirth Study MiNESS - The Midlands and North of England Stillbirth Study MiNESSIn Set-Up Pending NHS PermissionObservationalYes, within lead country only
 The ONE Study Cell Therapy Trial - A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ TransplantationIn Set-Up Pending NHS PermissionInterventionalNo
 The Pleth Variability Index and hypotension at caesarean under spinal. - Can changes in the Pleth Variability Index be used to predict significant hypotension during spinal anaesthesia for Caesarean section?In Set-Up Pending NHS PermissionObservationalNo
 The role of Nm23-H1 as a haemopoietic stem cell survival factor - The role of Nm23-H1 as a haemopoietic stem cell survival factor and its implications for leukaemiaIn Set-Up Pending NHS PermissionObservational 
 The TARGET Trial - A Phase I study of a chemotherapy doublet (Gemcitabine plus Capecitabine-GemCap) combined with a biologic doublet (Bevacizumab plus Erlotinib) in patients with advanced pancreatic adenocarcinoma (PC): the TARGET TrialIn Set-Up NHS Permission Received  
 The Veteran Athlete's Heart (Version 2) - The Veteran Athlete's HeartIn Set-Up NHS Permission ReceivedObservationalNo
 Trajectories of Outcome in Neurological Conditions Sub-Study 4 Longtitudinal - Trajectories of Outcome in Neurological Conditions: Quality of Life (QoL) and neurological disease Sub-Study4 LongtitudinalIn Set-Up Pending NHS PermissionObservationalYes, within lead country only
 Trial Net Dried Blood Spot Substudy - Dried Blood Spot Substudy to Assess the Use of Dried Capillary Bloodspots for Initial Screening to Identify Individuals with Multiple Islet AutoantibodiesIn Set-Up Pending NHS Permission  
 TRIP - Testing in recreational settings prevention - interventions addressed to polydrug users - TRIP - Testing in recreational settings prevention - interventions addressed to polydrug usersClosedObservationalN/A
 Understanding Treatment of Infection after Joint Replacement (v1.0) - Understanding the experience and provision of surgical treatment for prosthetic joint infection: a qualitative studyIn Set-Up Pending NHS PermissionObservationalNo
 Validation of a UK on-line 24h dietary recall tool - Validation of a UK on-line 24h dietary recall tool (MyFood24) for large scale population studiesIn Set-Up Pending NHS PermissionObservationalNo
 Validation of alcohol screening instruments in primary care - Alcohol Use Disorders Identification Test (AUDIT) and a shortened version (AUDITC) as screening instruments for identfication of excessive drinking: validation in a primary care population in EnglandIn Set-Up Pending NHS Permission  
 Well-being in pregnancy - Well-being in pregnancy: identification and prevalence of common mental health problemsIn Set-Up Pending NHS PermissionObservationalNo
 Welsh BDI study - Translation and Validation study of a Welsh Language Version of the Beck Depression Inventory-II.In Set-Up NHS Permission ReceivedObservational-unknown-
 White matter connections and memory: the STRATEGIC study - White matter connections and memory: the STRATEGIC studyIn Set-Up Pending NHS Permission  
 White Matter Mapping (06RP01) - White Matter Mapping for Improved Characterisation and Neurosurgical Planning of Brain TumoursIn Set-Up NHS Permission Received  
 Zibotentan better renal scleroderma outcome study (ZEBRA) - A phase II, single centre, randomised, placebo-controlled, 3-part trial to assess the safety, tolerability and efficacy of Zibotentan in patients with renal disease secondary to sclerodermaIn Set-Up Pending NHS PermissionInterventionalNo




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