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Export to Excel ISRCTN Acronym & Title Status Type Open to additional sites   ACTIVE SURVEILLANCE - A study of active surveillance for early prostate cancer Open not specified No   BiPAS - The Birmingham Prostatic Neoplasms Association Study - A genetic and environmental case control study on prostate cancer in Birmingham Open Observational No   BUMPS - Behavioural Urinary Management for Prostate Symptoms: A phase II trial for testing feasibility of a self-management intervantion for urinary problems following prostate radiotherapy Closed Interventional N/A   Cardiovascular Prostate Study - An open study of cardiovascular and osteoporotic risk factors in patients undergoing androgen deprivation therapy for prostate cancer. Closed Observational N/A 97182923 CHHIP - Conventional or Hypofractionated High Dose Intensity Modulated Radiotherapy for Prostate Cancer Open Interventional No   Coping with Cancer - Socio-economic Status and Coping with Cancer – Examining the Experience of People Recently Diagnosed with Cancer Closed Observational N/A   CV247 - A randomised double-blind local phase III study of CV247 vs salicyclic acid in early prostate cancer Closed Interventional N/A 13255144 DA v DAS in prostate cancer - A Randomised Phase III Trial of Dexamethasone and Aspirin (DA) Versus Dexamethasone, Diethylstilbestrol and Aspirin (DAS) in Locally Advanced or Metastatic Cancer of the Prostate Closed Interventional N/A   DB4 - Cancer Research UK Phase 1 Trial of 99mTc Demobesin-4 (99mTc DB4) given once via bolus intravenous injection for imaging of prostate cancer in Set-up Interventional No   EORTC 22991 - Three Dimensional Conformal Radiotherapy / Intensity Modulated Radiotherapy alone vs Three Dimensional Conformal Radiotherapy / Intensity Modulated Radiotherapy plus adjuvant hormonal therapy in localised T1b-c, T2a, N0, M0 prostatic carcinoma. Closed Interventional N/A   EORTC 30985 - Intermittent androgen deprivation in patients with stage D2 prostate cancer-Phase III Closed Interventional N/A   Flomax - Prophylactic Flomax in prostate cancer Closed Interventional N/A 69304414 FOCAL - HIFU - An Evaluation of Focal Ablation Therapy using High-Intensity Focused Ultrasound in the Treatment of Localized Adenocarcinoma of the Prostate Open Interventional No 25145525 HEMI-HIFU - An evaluation of hemi-ablation therapy using high-Intensity focused ultrasound in the treatment of localised adenocarcinoma of the prostate Closed Interventional N/A   High Dose Rhenium - High Activity Rhenium-186 HEDP with peripheral blood stem cell support in patients with bony metastases in prostate cancer. Closed Interventional N/A   HIPRO - Hypofractionated Dose Escalation utilising Intensity Modulated Radiotherapy (IMRT) in Carcinoma of the Prostate Closed Interventional N/A   IHT in prostate cancer - Intermittent androgen deprivation in patients with prostate cancer Closed Interventional N/A   IMPACT - Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted Screening in BRCA1/2 mutation carriers and controls - IMPACT Open Observational Yes, within and outside lead country 22761545 Intercontinental - INTERmittent or CONTINuos ENdocrine Therapy After failure in Localised prostate cancer. Closed Interventional N/A   Lesion Control HIFU - An Evaluation of Lesion Control using Focal Ablation with High Intensity Focused Ultrasound in the Treatment of Non-Metastatic Progressive Prostate Cancer Open Interventional No 59410552 LOPERA - Randomised controlled trial of laparoscopic, open and robot assisted prostatectomy as treatment for organ-confined prostate cancer. Open Interventional No 87696430 MAPS - Conservative treatment for urinary incontinence in Men After Prostate Surgery (MAPS): multicentre randomised controlled trial of pelvic floor muscle training, biofeedback and bladder training Closed Interventional N/A   Matched pair QoL/Toxicity Study in Advanced Prostate Cancer - Matched pair study to assess the quality of life and toxicity in patients with carcinoma of the prostate undergoing external beam radiotherapy plus high dose rate brachytherapy boost compared with patients receiving conformal external beam radiotherapy alone Open Observational No   NCRN001 (Onyvax P) - NCRN001 (Onyvax P) Closed Interventional N/A   NCRN018 - INDUSTRY STUDY - A Multicenter, Randomized, Double-Blind Study Comparing The Efficacy And Safety Of Aflibercept Versus Placebo Administered Every 3 Weeks In Patients Treated With Docetaxel / Prednisone For Metastatic Androgen-Independent Prostate Cancer Closed Interventional N/A   NCRN049 - A multicenter, randomized, double-blind, phase 3 study of sunitinib plus prednisone versus prednisone in patients with progressive metastatic hormone-refractory prostate cancer after failure of a docetaxel-based chemotherapy regimen Open Interventional No   NCRN078 - An Open-label, Multicenter, Phase 2 Study of Single-agent CNTO 888 (an anti-CCL2 Monoclonal Antibody) for the Treatment of Subjects with Metastatic Castrate-Resistant Prostate Cancer Closed Observational N/A   NCRN102 - A Phase II Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Study the Efficacy and Safety of Bicalutamide With or Without Deforolimus in Men With Asymptomatic, Metastatic Castrate-Resistant Prostate Cancer Open Interventional No   NCRN111 - A Randomized, Double Blind, Phase 3 Trial Comparing Ipilimumab vs. Placebo Following Radiotherapy in Subjects with Castration Resistant Prostate Cancer That Have Received Prior Treatment with Docetaxel Open Interventional No   NCRN112 - A Randomised Double Blind, Placebo-controlled Study to Evaluate the Effect on Unassisted Erectile Function of the Early use of Tadalafil 5mg Once a day and Tadalafil 20mg On Demand Treatment for 9 months in Subjects Undergoing Bilateral Nerve Sparing Radical Prostatectomy (BNSRP). Open Interventional -unknown-   NCRN121 - A PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF DOCETAXEL AND PREDNISONE WITH OR WITHOUT LENALIDOMIDE IN SUBJECTS WITH CASTRATE-RESISTANT PROSTATE CANCER Open Interventional -unknown- 70406718 PATCH - Prostate Adenocarcinoma: TransCutaneous Hormones. A randomised-controlled trial of transcutaneous oestrogen patches versus LHRH analogues in prostate cancer. Open Interventional Yes, within lead country only   PCSS - The Prostate Cancer Symptoms Study Closed Interventional N/A   Pelvic IMRT for prostate cancer - A Phase 1 dose escalation study of the use of intensity modulated radiotherapy (IMRT) to treat the prostate and pelvic nodes in patients with prostate cancer Closed Interventional N/A 24991896 PR07 - A Randomised trial of Hormone Therapy plus Radical radiotherapy versus Hormone Therapy alone in Non-Metastatic Prostate Cancer Closed Interventional N/A   PRECIOUS - Improving the assessment and recording of cancer treatment effects Open Observational No   Process - Prostate Cancer in Ethnic Subgroups: A comparative study of Incidence, Clinical Presentation and access to Health Care in the UK (Process). Closed Observational N/A 95931417 ProDiet - The feasibility of an RCT in dietary interventions for men at high risk of prostate cancer Closed Interventional N/A   ProMPT - Molecular mechanisms of disease progression and the development of novel treatment strategies in advanced prostate cancer (Northern Prostate Cancer Collaborative (ProMPT)) Open Observational -unknown-   ProSTART - A PHASE III STUDY OF ACTIVE SURVEILLANCE THERAPY AGAINST RADICAL TREATMENT IN PATIENTS DIAGNOSED WITH FAVOURABLE RISK PROSTATE CANCER (START) Closed Interventional N/A   Prostate & Cognition - An exploratory pilot study to investigate whether hormonal therapy for prostate cancer has an adverse effect on cognition Closed Observational N/A 98241100 Prostate HDR brachytherapy boost trial - Randomised trial of interstitial brachythearpy as a component of radical radiotherapy for localised prostatic cancer Closed Interventional N/A 20141297 ProtecT - The ProtecT Trial - Evaluating the effectiveness of treatment for clinically localised prostate cancer Closed Interventional N/A   Proteins CTCF and BORIS as biomarkers in breast and prostate cancers - A study on the proteins CTCF and BORIS in breast and prostate samples: the assessment of the potential diagnostic and prognostic value of CTCF and BORIS as biomarkers in breast and prostate cancers Open Observational No   RAACS - Rural accessibility and cancer survival Closed Interventional N/A 40814031 RADICALS (MRC PR10) - Radiotherapy and Androgen Deprivation In Combination After Local Surgery Open Interventional Yes, within and outside lead country   RAPPER - Radiogenomics: assessment of polymorphisms for predicting the effects of radiotherapy Open Observational Yes, within lead country only 86185157 RIB - A multicentre randomised trial of single dose Radiotherapy compared to Ibandronate for localised metastatic bone pain Closed Interventional N/A 47772397 RT01 - A Randomised Trial of High Dose Therapy in Localised Cancer of the Prostate Using Conformal Radiotherapy Techniques Closed Interventional N/A 88144169 SABRE 1 - Surgery And Brachytherapy - A Randomised Evaluation Randomised controlled trial of brachytherapy versus radical prostatectomy in good risk prostate cancer: a feasibility study Open Interventional No   SPIRIT - A Randomized Trial of Radical Prostatectomy versus Brachytherapy for Patients with T1c or T2a N0 M0 Prostate Cancer Closed Interventional N/A 78818544 Stampede - Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy Open Interventional Yes, within and outside lead country   TAPS - Targeted PSA screening for familial prostate cancer Closed Interventional N/A 12808747 TRAPEZE - A randomised phase II/III trial of docetaxel plus prednisolone vs. docetaxel plus prednisolone plus zoledronic acid vs. docetaxel plus prednisolone plus strontium-89 vs. docetaxel plus prednisolone plus zoledronic acid plus strontium-89 in hormone refractory prostate cancer metastatic to bone. Open Interventional Yes, within and outside lead country   UK Genetic Prostate Cancer Study - UK Genetic Prostate Cancer Study Open Observational Yes, within and outside lead country