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CogWatch v3 aw

CogWatch v3 aw

Portfolio Eligibility
Adopted non-commercial study
UKCRN ID 13369
Research Summary
The overall goal is to develop rehabilitation for stroke patients who have cognitive difficulty in performing activity of daily living (ADL) tasks, such as preparing a cup of tea. These difficulties, termed apraxia or action disorganisation syndrome (AADS), are distinct from hemiparesis. The first objective of the project is to develop a new cognitive approach to rehabilitation based on multimodal cueing of actions during ADL task performance. The second objective is to relate impairment in ADL task performance to brain function. Testing for the Birmingham Cognitive Screen (BCOS) has shown upto two thirdsof stroke patients meet the criteria for AADS, which can result in loss of independence. Previous research has shown that AADS patients respond to cognitive approaches to therapy and make shortterm improvements. However, the current lack of systematic classification of AADS, and the time consuming nature of ADL tasks, which makes patient retraining by therapists labour intensive, is an obstacle to the development of effective rehabilitation which this project seeks to redress. The project is in two phases. The first phase, for which ethical approval is now sought, focuses on making a hot drink and involves six sessions at the University of Birmingham. The first two sessions comprise assessment using both behavioural and neuroimaging methods. The second two sessions focus on contrasting methods of training sequential task performance with a group of patients who meet the criteria for AADS following stroke. The last two sessions involve assessment of a computerbased action recognition system for AADS treatment. The system will monitor progress and provide cues to prompt correct actions whenever errors are detected. The second phase, for which ethical approval will be sought later pending the results of the first phase, will involve a further feasibility study to compare two contrasting forms of cueing delivered by the computerbased system.
Study Type Interventional
Design Type Not specified
Disease(s) Therapy type
Phase Pilot/Feasibility
Current Status Closed - in follow-up
Closure Date 3/31/2015
Global Sample Size 50
Global Recruitment to Date
Geographical Scope UK Multi-Centre
Lead Country England
Main Inclusion Criteria
(i) adults aged 18-80 years
(ii) 14 days after stroke confirmed by MRI or CT scan.
(iii) impairment in one or more of the BCOS praxis items
(iv) ability to concentrate on simple practical tasks for 30 minutes.
Main Exclusion Criteria
(i) musculoskeletal disorder of the upper limb that could affect the ovement of the nonparetic upper limb
(ii) unstable blood pressure
(iii) visual problem affecting the handling of everyday objects
(iv) severe pain in the hemiplegic upper limb (more than 8/10 in VAS scale).
(v) contraindications for MRI (e.g., Pacemaker, claustrophobia)
Chief Investigator(s)
Prof A Wing
Further details, please contact
Ms Winnie Chua

University of Birmingham
School of Psychology
West Midlands
B15 2TT

Tel: 0121 414 2870
Ms Rosanna Laverick

University of Birmingham
School of Psychology
West Midlands
B15 2TT

Tel: 07852985370
Funder(s) European Comission Health Co-operation Programme of the 7th Framework Programme
Sponsor(s) University of Birmingham
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