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| NB: The information displayed below does not replace the protocol. The latest protocol version should always be consulted before making clinical decisions. |
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STROKE-INF
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A cluster randomised trial of different strategies of antibiotic use to reduce the incidence and consequences of chest infection in acute stroke patients with swallowing problems
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Topic
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Stroke
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Portfolio Eligibility
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Funded by UKCRC partner
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ISRCTN
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37118456
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EudraCT
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2007-004298-24
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MREC N° |
08/H0803/1
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UKCRN ID |
4458
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WHO ID
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Study Type |
Interventional
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Design Type |
Prevention, Process of Care, Treatment
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Disease(s) |
In hospital study
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Phase |
IV
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Current Status
| Open |
| Closure Date | 31/03/2012 |
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Sample Size
| 1200 |
| Accrual to Date |
 0% |
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Geographical Scope
| UK Multi-Centre |
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Lead Country
| England |
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Open to new sites
| Yes, within lead country only |
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Main Inclusion Criteria
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Ischaemic or hemorrhagic stroke patients within 48 hours of symptom onset, who are unable to swallow because of impaired consciousness levels or have failed the clinical bedside swallowing assessment performed by a trained professional.
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Main Exclusion Criteria
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1)age <18 years
2)pre-existing swallowing problems
3)evidence of infection or pyrexia at the time of admission
4)allergy to penicillin’s or macrolides
5)pregnant and lactating women
6)antibiotic treatment within the week prior to inclusion
7)lack of consent from the patient or next of kin
8)expected survival <2 weeks
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Chief Investigator(s)
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| Prof Lalit Kalra |
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Further details, please contact
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Prof Lalit Kalra
King's College Hospital NHS Trust
King's College Hospital NHS Trust
Bessemer Road
London
SE5 9PJ
UNITED KINGDOM
Tel: 020 3299 1718
lalit.kalra@kcl.ac.uk
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Funder(s) |
NIHR
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Sponsor(s) |
King College Hospital and Kings College London
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