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Omega 3 Fatty Acids in Skin Cell Protection from Sunlight

Omega 3 Fatty Acids in Skin Cell Protection from Ultraviolet Damage

Specialty
Dermatology
Portfolio Eligibility
Automatically eligible
ISRCTN 04778461
EudraCT
MREC N° 08/H1004/19
UKCRN ID 4953
WHO ID
Research Summary
Examination into the photoproptective potential of topically applied omega-3 fatty acids. Changes in the parameters of short and long term UV-damage will be assessed. This includes analysis of the sunburn response, bioavailability of fatty acids, expression of lipid mediators and expression of p53 and collagen.
Study Type Interventional
Design Type Not specified
Disease(s) Dermatology
Phase Pilot/Feasibility
Current Status Closed - follow-up complete
Closure Date 9/30/2011
Global Sample Size 64
Global Recruitment to Date
  73%
Geographical Scope Single Centre
Lead Country England
Main Inclusion Criteria
Whit Caucasian
Aged between 20 and 60 years old
Skin type 1 to 3
Main Exclusion Criteria
Taking photoactive or anti inflammatory medication
History of photosensitivity
History of skin cancer
Pregnant or breast feeding
Taking omega-3 supplements
Sunbathed in past 3 months
Chief Investigator(s)
Prof Lesley Rhodes
Further details, please contact
Dr Mark Farrar

Salford Royal NHS Foundation Trust
Photobiology Unit
Hope Hospital
Stott Lane
Salford
Greater Manchester
M6 8HD
UNITED KINGDOM

Tel: 0161 2060214
Fax: 0161 2061156
mark.farrar@manchester.ac.uk
Miss Suzanne Pilkington

Salford Royal Foundation Hospital
Photobiology Unit, Dermatological Sciences,

Hope Hospital
Stott Lane
Salford
Greater Manchester
M6 8HD
UNITED KINGDOM

Tel: 0161 206 1150
Suzanne.Pilkington@manchester.ac.uk
Funder(s) Biotechnology and Biological Sciences Research Council (BBSRC)
Croda International Plc
Sponsor(s) University of Manchester




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